Browsing by Subject "Databases, Genetic"

Now showing items 1-3 of 3

    • Article  

      The cypriot and Iranian National Mutation Frequency Databases. 

      Kleanthous, Marios; Patsalis, Philippos C.; Drousiotou, Anthi; Motazacker, M.; Christodoulou, Kyproula; Cariolou, Marios A.; Baysal, E.; Khrizi, K.; Moghimi, B.; Pourfarzad, F.; van Baal, S.; Constantinou-Deltas, Constantinos D.; Najmabadi, H.; Patrinos, G. P. (2006)
      The National Mutation Frequency Databases are continuously updated mutation depositories, which contain extensive information over the described genetic heterogeneity of an ethnic group or population. Here, we report the ...
    • Article  

      Increased number of MicroRNA target sites in genes encoded in CNV regions. Evidence for an evolutionary genomic interaction 

      Felekkis, Kyriacos N.; Voskarides, Konstantinos; Dweep, H.; Sticht, C.; Gretz, N.; Constantinou-Deltas, Constantinos D. (2011)
      MicroRNAs (miRNAs) and copy number variations (CNVs) are two newly discovered genetic elements that have revolutionized the field of molecular biology and genetics. By performing in silico whole genome analysis, we demonstrate ...
    • Article  

      The interplay between DSL proteins and ubiquitin ligases in Notch signaling 

      Pitsouli, Chrysoula; Delidakis, Christos (2005)
      Lateral inhibition is a pattern refining process that generates single neural precursors from a field of equipotent cells and is mediated via Notch signaling. Of the two Notch ligands Delta and Serrate, only the former was ...